Pseudoaneurysm of the Peroneal Artery: Presentation of Ehlers-Danlos Syndrome Type IV
Received 4 December 2007; accepted 23 February 2008. published online 16 May 2008.
Abstract
Introduction
Pseudoaneurysms in deep or unusual sites raise the possibility of an underlying vessel wall disorder.
Report
A 28-year-old woman presented with pain and swelling of her calf, with no history of trauma. Angiography diagnosed a peroneal artery pseudoaneurysm, which we embolised successfully. Subsequent genetic analysis revealed the COL3A1 mutation, confirming Ehlers-Danlos syndrome type IV.
Conclusion
To our knowledge, this is the first report of a peroneal artery pseudoaneurysm associated with underlying collagen vascular disease.
aSt Mary's Hospital, South Wharf Road, Paddington, London W2 1NY, United Kingdom
bNorthwick Park Hospital, Watford Road, Harrow, Middlesex HA1 3UJ, United Kingdom
cNorth West Thames Regional Genetics Service, (Kennedy-Galton Centre), NWLH NHS Trust, Watford Road, Harrow HA1 3UJ, United Kingdom
Corresponding author. Dr. K. Mandeville, St Mary's Hospital, South Wharf Road, Paddington, London W2 INY, UK. Tel.: +44 208 450 2055; fax:+44 208 869 2577.
ABSTRACT