European Journal of Vascular & Endovascular Surgery
Volume 31, Issue 3 , Pages 244-250 , March 2006

Homocysteine Levels, Haemostatic Risk Factors and Patency Rates After Endovascular Treatment of the Common Iliac Arteries

  • E. Laxdal

      Affiliations

    • Department of Vascular Surgery, Haukeland University Hospital, Bergen, Norway
    • Department of Surgical Research, University of Bergen, Bergen, Norway
    • Corresponding Author InformationCorresponding author. Dr E. Laxdal, MD, Department of Vascular Surgery, Haukeland University Hospital, Bergen, Norway.
    • ,
  • J. Wirsching

      Affiliations

    • Department of Radiology, Haukeland University Hospital, Bergen, Norway
    • ,
  • G. Pedersen

      Affiliations

    • Department of Vascular Surgery, Haukeland University Hospital, Bergen, Norway
    • ,
  • A. Bertz

      Affiliations

    • Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    • ,
  • S.R. Amundsen

      Affiliations

    • Department of Vascular Surgery, Haukeland University Hospital, Bergen, Norway
    • ,
  • E. Dregelid

      Affiliations

    • Department of Vascular Surgery, Haukeland University Hospital, Bergen, Norway
    • ,
  • T. Jonung

      Affiliations

    • Department of Surgical Research, University of Bergen, Bergen, Norway
    • ,
  • T. Nyheim

      Affiliations

    • Department of Vascular Surgery, Haukeland University Hospital, Bergen, Norway
    • ,
  • S. Aune

      Affiliations

    • Department of Vascular Surgery, Haukeland University Hospital, Bergen, Norway

,Accepted 27 June 2005.

References 

  1. Bosch JL, Hunink MG. Meta-analysis of the results of percutanous transluminal angioplasty and stent placement for aortoiliac occlusive disease. Radiology. 1997;204:87–96
  2. Becquemin JP, Allaire E, Qvarfordt P, Desgranges P, Kolbeiter HM. Surgical transluminal iliac angioplasty with selective stenting: long-term results assessed by means of duplex scanning. J Vasc Surg. 1999;29:422–429
  3. Glacov S. Intimal hyperplasia, vascular modelling and restenosis problem. Circulation. 1994;89:2888–2891
  4. Haudenschild CC. Pathobiology of restenosis after angioplasty. Am J Med. 1993;94(Suppl 4A):40s–44s
  5. van Goor H, Boontje AH. Results of vascular reconstructions for atherosclerotic arterial occlusive disease of the lower limbs in young adults. Eur J Vasc Endovasc Surg. 1995;10(3):323–326
  6. Aune S, Laxdal E. Above-knee prosthetic femoropopliteal bypass for intermittent claudication. Results of the initial and secondary procedures. Eur J Vasc Endovasc Surg. 2000;19(5):476–480
  7. Laxdal E, Jenssen GL, Pedersen G, Aune S. Subintimal angioplasty as a treatment of femoropopliteal artery occlusions. Eur J Vasc Endovasc Surg. 2003;25(6):578–582
  8. Olojugba DH, McCarthy MJ, Reid A, Varty K, Naylor AR, Bell PR, et al. Infrainguinal revascularisation in the era of vein-graft surveillance—do clinical factors influence long-term outcome?. Eur J Vasc Endovasc Surg. 1999;17(2):121–128
  9. Laxdal E, Eide GE, Wirsching J, Jenssen GL, Jonung T, Pedersen G, et al. Homocysteine levels, haemostatic risk factors and patency rates after endovascular treatment of the above-knee femoro-popliteal artery. Eur J Vasc Endovasc Surg. 2004;28(4):410–417
  10. Schillinger M, Exner M, Mlekusch W, Rumpold H, Ahmadi R, Sabethi S, et al. Fibrinogen predicts restenosis after endovascular treatment of the iliac arteries. Thromb Haemost. 2002;87:959–965
  11. Sampram ESK, Lindblad B, Dahlbäck B. Activated protein C resistance in peripheral vascular disease. J Vasc Surg. 1998;28:624–629
  12. Taylor LM, DeFrang RD, Harris EJ, Porter JM. The association of elevated plasma homocysteine with progression of symptomatic pheripheral artery disease. J Vasc Surg. 1991;13:128–136
  13. Lange H, Suryapranata H, De Luca G, Borner C, Dille J, Kallmayer K, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med. 2004;350(26):2673–2681
  14. Schnyder G, Roffi M, Flammer Y, Pin R, Hess OM. Association of plasma homocysteine with restenosis after percutaneous coronary angioplasty. Eur Heart J. 2002;23(9):726–733
  15. de Borst GJ, Tangelder MJD, Algra A, Lawson JA, Banga JD, Eikelboom BC, et al. The influence of hyperhomocysteinemia on graft patency after infrainquinal bypass surgery in the Dutch BOA Study. J Vasc Surg. 2002;36:336–340
  16. Beattie DK, Sian M, Greenhalg RM, Davies AH. Influence of systemic factors on pre-existing intimal hyperplasia and their effect on the outcome of infraiguinal arterial re-construction with vein. Br J Surg. 1999;86:1441–1447
  17. Irvine C, Wilson YG, Currie IC, McGrath C, Scott J, Day A, et al. Hyper-homocysteinemia is a risk factor for vein graft stenosis. Eur J Vasc Endovasc Surg. 1996;12:304–309
  18. Currie IC, Wilson YG, Scott J, Day A, Stansbie D, Baird RN, et al. Homocysteine: an independent risk factor for the failure of vascular intervention. Br J Surg. 1996;(83):1238–1241
  19. Laxdal E, Eide GE, Amundsen SR, Dregelid EB, Pedersen G, Jonung T, et al. Homocysteine levels, haemostatic risk factors and restenosis after carotid thrombendarterectomy. Eur J Vasc Endovasc Surg. 2004;28:323–328
  20. Samson RH, Yungst Z, Showalter DP. Homocysteine, a risk factor for carotid atherosclerosis, is not a risk factor for early recurrent carotid stenosis following carotid endarterectomy. Vasc Endovascular Surg. 2004;38(4):345–348
  21. Kovacevic T, Van Der Loo B, Amann-Vesti BR, Rousson V, Koppensteiner R. Plasma homocysteine and restenosis after femoropopliteal angioplasty. Endovasc Ther. 2004;11(3):302–309
  22. Tsakiris DA, Tschøpl M, Jäger K, Haefeli WE, Wolf F, Marbet GA. Circulating cell adhesion molecules and endothelial markers before and after transluminal angioplasty in peripheral arterial occlusive disease. Atherosclerosis. 1999;142:193–200
  23. Osterberg K, Mattsson E. Intimal hyperplasia in mouse vein grafts is regulated by flow. J Vasc Res. 2005;42(1):13–20[Epub 2004 Dec 17]
  24. Fernandez CM, Goldman DR, Jiang Z, Ozaki CK, Tran-Son-Tay R, Berceli SA. Impact of Shear stress on early vein graft remodeling: a biomechanical analysis. Ann Biomed Eng. 2004;32(11):1484–1493
  25. Schillinger M, Exner M, Mlekusch W, Haumer M, Ahmadi R, Rumpold H, et al. Inflammatory response to stent implantation: differences in femoropopliteal, iliac and carotid arteries. Radiology. 2002;224(2):529–535
  26. Royo T, Martinez-Gonzàlez J, Vilahur G, Badimon L. Differential intracellular trafficking of von Willebrand factor (vWF) and vWF propeptide in porcine endothelial cells lacking Weibel–Palade bodies and in human endothelial cells. Atherosclerosis. 2003;167:55–63
  27. Tetteroo E, Haaring C, van der Graaf Y, van Schaik JP, van Engelen AD, Mali WP. Intrarterial pressure gradients after randomized angioplasty or stenting of iliac artery lesions. Dutch Iliac Stent Trial Study Group. Cardiovasc Intervent Radiol. 1996;19:411–417
  28. Second European Consensus Document on chronic critical leg ischaemia. Eur J Vasc Surg 1992;6:1–32.
  29. Dotter CT, Judkins MP. Transluminal treatment of atherosclerotic obstructions. Description of a new technique and a preliminary report of its application. Circulation. 1964;30:654
  30. Hennerici M, Neuerburger-Heusler D. Vascular diagnosis with ultrasound. Stuttgart, New York: Thieme Medical Publishers; 1998;
  31. Greiner A, Dessl A, Klein-Weigel P, Neuhauser B, Perkmann R, Waldenberger P, et al. Kissing stents for treatment of complex aortoiliac disease. Eur J Vasc Endovasc Surg. 2003;26(2):161–165
  32. Koelemay MJ, den Hartog D, Prins MH, Kromhout JG, Legemate DA, Jacobs MJ. Diagnosis of arterial disease of the lower extremities with duplex ultrasonograhy. Br J Surg. 1996;83:404–409
  33. McCully KS. Vascular pathology of homocysteinemia: implications for the pathogenesis of atherosclerosis. Am J Patholog. 1969;56:111–128
  34. Refsum H, Nygard O, Kvale G, Ueland PM, Vollset SE. The Hordaland homocysteine study: the opposite tails odds ratios reveal differential effects of gender and intake of vitamin supplements at high and low plasma total homocysteine concentrations. J Nutr. 1996;126(Suppl 4):1244S–1248S
  35. Vollset SE, Refsum H, Tverdal A, Nygard O, Nordrehaug JE, Tell GS, et al. Plasma total homocysteine and cardiovascular and noncardiovascular mortality: the Hordaland Homocysteine Study. Am J Clin Nutr. 2001;74(1):130–136
  36. Hoogeveen EK, Kostense PJ, Jakobs C, Rauwerda JA, Dekker JM, Nijpels G, et al. Hyperhomocysteinaemia is not associated with isolated crural arterial occlusive disease: The Hoorn Study. J Int Med. 2000;247(4):442–448
  37. Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for systemic atherosclerosis. A comparison of C-reactive protein, fibrinogen, homocysteine lipoprotein (a), and standard cholesterol screening as predictors for pheripheral arterial disease. JAMA. 2001;285:2481–2485
  38. Symonides B, Januszewicz A, Rowinski O, Januszewicz M, Chodakowska J, Berent H, et al. Plasma fibrinogen as a risk factor for restenosis after percutaneous transluminal renal angioplasty in patients with atherosclerotic renal artery stenosis. J Cardiovasc Risk. 1999;6(4):269–272
  39. Avci A, Boyaci A, Cagli K, Cosgun A, Gokce V, Duru E, et al. Influence of haematological parameters before coronary angioplasty on subsequent restenosis. Acta Cardiol. 2004;59(3):263–268
  40. Otsuka M, Hayashi Y, Ueda H, Imazu M, Kohno N. Predictive value of preprocedural fibrinogen concerning coronary stenting. Atherosclerosis. 2002;164(2):371–378
  41. Volzke H, Grimm R, Robinson DM, Wolff B, Schwahn C, Hertwig S, et al. Candidate genetic markers and the risk of restenosis after coronary angioplasty. Clin Sci (London). 2004;106(1):35–42
  42. Montalescot G, Ankri A, Vicaut E, Drobinski G, Grosgogeat Y, Thomas D. Fibrinogen after coronary angioplasty as a risk factor for restenosis. Circulation. 1995;92(1):31–38
  43. Price JF, Mamode N, Smith FB, Woodburn KR, Rumley A, Lowe GD, et al. Haemostatic and rheological factors as predictors of restenosis following percutaneous transluminal angioplasty. Eur J Vasc Endovasc Surg. 1997;14(5):392–398
  44. Tschopl M, Tsakiris DA, Marbet GA, Labs KH, Jager K. Role of hemostatic risk factors for restenosis in peripheral arterial occlusive disease after transluminal angioplasty. Arterioscler Thromb Vasc Biol. 1997;17(11):3208–3214
  45. Tsakiris DA, Tschopl M, Wolf F, Labs KH, Jager KA, Marbet GA. Platelets and cytokines in concert with endothelial activation in patients with peripheral arterial occlusive disease. Blood Coagul Fibrinolysis. 2000;11(2):165–173
  46. van der Loo B, Kovacevic T, Krieger E, Banyai S, Banyai M, Amann-Vesti BR, et al. Blood fluidity and outcome after femoropopliteal percutaneous transluminal angioplasty (PTA): role of plasma viscosity and low platelet count in predicting restenosis. Clin Hemorheol Microcirc. 2005;32(2):159–168
  47. Schillinger M, Haumer M, Schlerka G, Mlekusch W, Exner M, Ahmadi R, et al. Restenosis after percutaneous transluminal angioplasty in the femoropopliteal segment: the role of inflammation. J Endovasc Ther. 2001;8(5):477–483
  48. Schillinger M, Exner M, Mlekusch W, Rumpold H, Ahmadi R, Sabeti S, et al. Vascular inflammation and percutaneous transluminal angioplasty of the femoropopliteal artery: association with restenosis. Radiology. 2002;225(1):21–26
  49. Prisco D, Antonucci E, Fedi S, Margheri M, Giglioli C, Comeglio M, et al. D-dimer increase after percutaneous transluminal angioplasty and clinical recurrence after primary revascularization in acute myocardial infarction? A pilot study. Clin Exp Med. 2001;1(4):219–224

PII: S1078-5884(05)00629-5

doi: 10.1016/j.ejvs.2005.06.032

European Journal of Vascular & Endovascular Surgery
Volume 31, Issue 3 , Pages 244-250 , March 2006

Article Tools

* Image Usage & Resolution