European Journal of Vascular & Endovascular Surgery
Volume 31, Issue 3 , Pages 274-279 , March 2006

Efficacy of Vancomycin, Teicoplanin and Fusidic Acid as Prophylactic Agents in Prevention of Vascular Graft Infection: An Experimental Study in Rat

  • A. Yasim

      Affiliations

    • Department of Cardiovascular Surgery, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Turkey
    • Corresponding Author InformationCorresponding author. Alptekin Yasim, MD, Department of Cardiovascular Surgery, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaraş, Turkey.
    • ,
  • M. Gul

      Affiliations

    • Department of Microbiology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Turkey
    • ,
  • E. Atahan

      Affiliations

    • Department of Cardiovascular Surgery, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Turkey
    • ,
  • P. Ciragil

      Affiliations

    • Department of Microbiology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Turkey
    • ,
  • M. Aral

      Affiliations

    • Department of Microbiology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Turkey
    • ,
  • Y. Ergun

      Affiliations

    • Department of Pharmacology, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Turkey

,Accepted 23 September 2005.

References 

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  2. Lehnhardt FJ, Torsello G, Claeys LGY, Pfeiffer M, Wachol-Drewek Z, Grundmann RT, et al. Systemic and local antibiotic prophylaxis in the prevention of prosthetic vascular graft infection: an experimental study. Eur J Vasc Endovasc Surg. 2002;23:127–133
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  9. Sago T, Mori Y, Takagi H, Iwata H, Murase K, Kawamura Y, et al. Local treatment of Dacron patch graft contaminated with Staphylococcus aureus with antibiotic-releasing porous apatite ceramic: an experimental study in the rabbit. J Vasc Surg. 2003;37:169–174
  10. Gabriel M, Pukacki F, Dzieciuchowicz L, Oszkinis G, Checinski P. Cryopreserved arterial allografts in the treatment of prosthetic graft infections. Eur J Vasc Endovasc Surg. 2004;27:590–596
  11. Henke PK, Bergamini TM, Rose SM, Richardson JD. Current options in prosthetic vascular graft infection. Am Surg. 1998;64:39–46
  12. Ghiselli R, Giacometti A, Cirioni O, Mocchegiani F, Orlando F, Del Prete MS, et al. Quinupristin/dalfopristin bonding in combination with intra-peritoneal antibiotics prevent infection of knitted polyester graft material in a subcutaneous rat pouch model infected with resistant Stapylococcus epidermidis. Eur J Vasc Endovasc Surg. 2002;24:230–234
  13. Ghiselli R, Giacometti A, Goffi L, Cirioni O, B¨occoli G, Mocchegiani F, et al. Efficacy of rifampin–levofloxacin as a prophylactic agent in preventing Staphylococcus epidermidis graft infection. Eur J Vasc Endovasc Surg. 2000;20:508–511
  14. Giacometti A, Cirioni O, Ghiselli R, Goffi L, Mocchegiani F, Riva A, et al. Policationic peptides as prophylactic agents against methicillin-susceptible or methicillin-resistant Staphylococcus epidermidis vascular graft infection. Antimicrob Agents Chemother. 2000;44:3306–3309
  15. Giacometti A, Cirioni O, Ghiselli R, Goffi L, Mocchegiani F, Riva A, et al. Efficacy of polycationic peptides in preventing vascular graft infection due to Staphylococcus epidermidis. J Antimicrob Chemother. 2000;46:751–756
  16. Ghiselli R, Giacometti A, Goffi L, Cirioni O, Mocchegiani F, Orlando F, et al. Prophylaxis against Staphylococcus aureus vascular graft infection with mupirocin-soaked, collagen-sealed Dacron. J Surg Res. 2001;99:316–320
  17. Naylor AR, Hayes PD, Darke S. A prospective audit of complex wound and graft infections in Great Britain and Ireland: the emergence of MRSA. Eur J Vasc Endovasc Surg. 2001;21:289–294
  18. Nasim A, Thompson MM, Naylor AR, Bell PRF, London NJM. The impact of MRSA on vascular surgery. Eur J Vasc Endovasc Surg. 2001;22:211–214
  19. Ghiselli R, Giacometti A, Cirioni O, Dell’Acqua G, Mocchegiani F, Orlando F, et al. RNAIII-inhibiting peptide and/or nisin inhibit experimental vascular graft infection with methicillin-susceptible and methicillin-resistant Staphylococcus epidermidis. Eur J Vasc Endovasc Surg. 2004;27:603–607
  20. Giacometti A, Cirioni O, Ghiselli R, Goffi L, Viticchi C, Mocchegiani F, et al. Mupirocin prophylaxis against methicillin-susceptible, methicillin-resistant, or vancomycin-intermediate Staphylococcus epidermidis vascular graft infection. Antimicrob Agents Chemother. 2000;44:2842–2844
  21. Cirioni O, Giacometti A, Ghiselli R, Dell’Acqua G, Gov Y, Kamysz W, et al. Prophylactic efficacy of topical temporin A and RNAIII-inhibiting peptide in a subcutaneous rat pouch model of graft infection attributable to staphylococci with intermediate resistance to glycopeptides. Circulation. 2003;108:767–771
  22. Ersoz G, Oztuna V, Coskun B, Eskandari MM, Bayarslan C, Kaya A. Addition of fusidic acid impregnated bone cement to systemic teicoplanin therapy in the treatment of rat osteomyelitis. J Chemother. 2004;16:51–55

PII: S1078-5884(05)00638-6

doi: 10.1016/j.ejvs.2005.09.018

European Journal of Vascular & Endovascular Surgery
Volume 31, Issue 3 , Pages 274-279 , March 2006

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