European Journal of Vascular & Endovascular Surgery
Volume 34, Issue 1 , Pages 10-17 , July 2007

New Antiplatelet Strategies in Atherothrombosis and Their Indications

  • P. Fontana

      Affiliations

    • Division of Angiology and Haemostasis, Department of Internal Medicine, Faculty of Medicine and University Hospitals of Geneva, Geneva, Switzerland
    • Corresponding Author InformationCorresponding author. Dr. Pierre Fontana, Division of Angiology and Haemostasis, University Medical Centre, 1 rue Michel-Servet, CH-1211 Geneva 14, Switzerland.
    • ,
  • J.-L. Reny

      Affiliations

    • Department of Internal Medicine, Centre Hospitalier de Béziers, 2 rue Valentin Hauÿ, BP 740, 34525 Béziers Cedex, France
    • Corresponding Author InformationCorresponding author. Dr. Jean-Luc Reny, Department of Internal Medicine, Centre Hospitalier de Béziers, 2 rue Valentin Hauÿ, 34525 Béziers Cedex, France.

,Accepted 18 January 2007.

  • Image Result

    Main amplification pathways of platelet activation and action of antiplatelet agents (APA). The two main amplification pathways are the thromboxane A2 (T×A2) and adenosine diphosphate (ADP) pathways,

    Main amplification pathways of platelet activation and action of antiplatelet agents (APA). The two main amplification pathways are the thromboxane A2 (T×A2) and adenosine diphosphate (ADP) pathways, which are targeted by the most widely used APAs. AA: arachidonic acid, cAMP: cyclic adenosine monophosphate, PDE: phosphodiesterases.

 One of a series of educational articles edited by Janet Powell, UK.

PII: S1078-5884(07)00060-3

doi: 10.1016/j.ejvs.2007.01.004

European Journal of Vascular & Endovascular Surgery
Volume 34, Issue 1 , Pages 10-17 , July 2007

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