European Journal of Vascular & Endovascular Surgery
Volume 35, Issue 2 , Pages 159-161 , February 2008

Low Molecular Weight Heparin Treatment Decreases MMP-9 Plasma Activity in Patients with Abdominal Aortic Aneurysm

  • T. Grzela

      Affiliations

    • Department of Histology and Embryology, Warsaw Medical University, Poland
    • Corresponding Author InformationCorresponding author. T. Grzela, MD, PhD, Department of Histology and Embryology, Biostructure Research Center at the Warsaw Medical University, Chalubinskiego 5, PL 02-004 Warsaw, Poland.
  • ,
  • R. Brawura-Biskupski-Samaha

      Affiliations

    • Department of Histology and Embryology, Warsaw Medical University, Poland
  • ,
  • M.M. Jelenska

      Affiliations

    • Department of General, Vascular and Transplant Surgery, Central University Hospital, Warsaw Medical University, Poland
  • ,
  • J. Szmidt

      Affiliations

    • Department of General, Vascular and Transplant Surgery, Central University Hospital, Warsaw Medical University, Poland

,Accepted 13 September 2007.

  • Image Result

    MMP-9 zymograms of AAA control group (panel A) and LMWH-treated AAA patients (panel B). Each band represents one individual's plasma sample, displaying MMP-9-specific activity, with the band thickness

    MMP-9 zymograms of AAA control group (panel A) and LMWH-treated AAA patients (panel B). Each band represents one individual's plasma sample, displaying MMP-9-specific activity, with the band thickness corresponding to the MMP-9 amount/activity. Each rectangle in panel B contains a pair of MMP-9 bands from one individual' plasma samples, before and after LMWH treatment, respectively. The calculated MMP-9 concentration (ng/ml) was shown in panel C. Squares represent patients from AAA control group, whereas circles represent LMWH-treated patients before (open circles) and after treatment (filled circles). In each group mean values have been shown as solid lines and median values are represented by dotted lines. NS – non significant.

PII: S1078-5884(07)00600-4

doi: 10.1016/j.ejvs.2007.09.008

European Journal of Vascular & Endovascular Surgery
Volume 35, Issue 2 , Pages 159-161 , February 2008