European Journal of Vascular & Endovascular Surgery
Volume 35, Issue 2 , Pages 159-161 , February 2008

Low Molecular Weight Heparin Treatment Decreases MMP-9 Plasma Activity in Patients with Abdominal Aortic Aneurysm

  • T. Grzela

      Affiliations

    • Department of Histology and Embryology, Warsaw Medical University, Poland
    • Corresponding Author InformationCorresponding author. T. Grzela, MD, PhD, Department of Histology and Embryology, Biostructure Research Center at the Warsaw Medical University, Chalubinskiego 5, PL 02-004 Warsaw, Poland.
    • ,
  • R. Brawura-Biskupski-Samaha

      Affiliations

    • Department of Histology and Embryology, Warsaw Medical University, Poland
    • ,
  • M.M. Jelenska

      Affiliations

    • Department of General, Vascular and Transplant Surgery, Central University Hospital, Warsaw Medical University, Poland
    • ,
  • J. Szmidt

      Affiliations

    • Department of General, Vascular and Transplant Surgery, Central University Hospital, Warsaw Medical University, Poland

,Accepted 13 September 2007.

References 

  1. Wilson WR, Anderton M, Schwalbe EC, Jones JL, Furness PN, Bell PR, et al. Matrix metalloproteinase-8 and –9 are increased at the site of abdominal aortic aneurysm rupture. Circulation. 2006;113:438–445
  2. Wassef M, Baxter BT, Chisholm RL, Dalman RL, Fillinger MF, Heinecke J, et al. Pathogenesis of abdominal aortic aneurysms: a multidisciplinary research program supported by the National Hearth, Lung, and Blood Institute. J Vasc Surg. 2001;34:730–738
  3. Baxter BT. Abdominal aortic aneurysm regression by medical treatment: possibility or pipe dream?. J Vasc Surg. 2006;43:1068–1069
  4. Jelenska MM, Szmidt J, Bojakowski K, Grzela T, Palester-Chlebowczyk M. Compensated activation of coagulation in patients with abdominal aortic aneurysm: effects of heparin treatment prior to elective surgery. Thromb Haemost. 2004;92:997–1002
  5. Ranjbaran H, Wang Y, Manes TD, Yakimov AO, Akhtar S, Kluger MS, et al. Heparin displaces interferon-gamma-inducible chemokines (IP-10, I-TAC, and Mig) sequestered in the vasculature and inhibits the transendothelial migration and arterial recruitment of T cells. Circulation. 2006;114:1293–1300

PII: S1078-5884(07)00600-4

doi: 10.1016/j.ejvs.2007.09.008

European Journal of Vascular & Endovascular Surgery
Volume 35, Issue 2 , Pages 159-161 , February 2008

Article Tools

* Image Usage & Resolution