European Journal of Vascular & Endovascular Surgery
Volume 38, Issue 5 , Pages 546-551 , November 2009

Carotid Endarterectomy Improves Cerebrovascular Reserve Capacity Preferentially in Patients with Preoperative Impairment as Indicated by Asymmetric BOLD Response to Hypercapnia

  • S.D. Goode

      Affiliations

    • Department of Academic Radiology, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
    • Department of Vascular and Endovascular Surgery, Queens Medical Centre, Nottingham NG7 2UH, UK
    • ,
  • N. Altaf

      Affiliations

    • Department of Academic Radiology, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
    • Department of Vascular and Endovascular Surgery, Queens Medical Centre, Nottingham NG7 2UH, UK
    • ,
  • D.P. Auer

      Affiliations

    • Department of Academic Radiology, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
    • Corresponding Author InformationCorresponding author.
    • ,
  • S.T.R. MacSweeney

      Affiliations

    • Department of Academic Radiology, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
    • Department of Vascular and Endovascular Surgery, Queens Medical Centre, Nottingham NG7 2UH, UK

Received 17 February 2009 ,Accepted 14 June 2009.

References 

  1. Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST). Lancet. 1998;351(9113):1379–1387
  2. Ferguson GG, Eliasziw M, Barr HW, Clagett GP. The North American Symptomatic Carotid Endarterectomy Trial: surgical results in 1415 patients. Stroke. 1999;30(9):1751–1758
  3. Markus H, Cullinane M. Severely impaired cerebrovascular reactivity predicts stroke and TIA risk in patients with carotid artery stenosis and occlusion. Brain. 2001;124(Pt 3):457–467
  4. Nemoto EM, Yonas H, Kuwabara H, Pindzola RR, Sashin D, Meltzer TC, et al. Identification of hemodynamic compromise by cerebrovascular reserve and oxygen extraction fraction in occlusive vascular disease. Journal of Cerebral Blood Flow and Metabolism. 2004;24(10):1081–1089
  5. Sedlaczek O, Caplan L, Hennerici M. Impaired washout-embolism and ischemic stroke: further examples and proof of concept. Cerebrovascular Diseases. 2005;19(6):396–401
  6. Barzo P, Voros E, Bodosi M. Use of transcranial Doppler sonography and acetazolamide test to demonstrate changes in cerebrovascular reserve capacity following carotid endarterectomy. European Journal of Vascular Endovascular Surgery. 1996;11(1):83–89
  7. Cikrit DF, Dalsing MC, Harting PS, Burt RW, Lalka SG, Sawchuk AP, et al. Cerebral vascular reactivity assessed with acetazolamide single photon emission computer tomography scans before and after carotid endarterectomy. American Journal of Surgery. 1997;174(2):193–197
  8. D’Angelo V, Catapano G, Bozzini V, Catapano D, De Vivo P, Ciritella P, et al. Cerebrovascular reactivity before and after carotid endarterectomy. Surgical Neurology. 1999;51(3):321–326
  9. Kawaguchi S, Sakaki T, Uranishi R. Effects of bypass on CO2 cerebrovascular reactivity in ischaemic cerebrovascular diseases Based on the intra-operative LCBF and CO2 cerebrovascular reactivity studies. Acta Neurochirurgica. 1999;141(4):369–374
  10. Lythgoe DJ, Williams SC, Cullinane M, Markus HS. Mapping of cerebrovascular reactivity using BOLD magnetic resonance imaging. Magnetic Resonance Imaging. 1999;17(4):495–502
  11. In:  Moonen CT editors. Functional MRI. Berlin: Springer; 2000;
  12. Van der Zande FH, Hofman PA, Backes WH. Mapping hypercapnia-induced cerebrovascular reactivity using BOLD MRI. Neuroradiology. 2005;47(2):114–120
  13. Vesely A, Sasano H, Volgyesi G, Somogyi R, Tesler J, Fedorko L, et al. MRI mapping of cerebrovascular reactivity using square wave changes in end-tidal PCO2. Magnetic Resonance in Medicine. 2001;45(6):1011–1013
  14. Ziyeh S, Rick J, Reinhard M, Hetzel A, Mader I, Speck O. Blood oxygen level-dependent MRI of cerebral CO2 reactivity in severe carotid stenosis and occlusion. Stroke. 2005;36(4):751–756
  15. Sidhu PS, Allan PL. Ultrasound assessment of internal carotid artery stenosis. Clincal Radiology. 1997;52(9):654–658
  16. Endovascular versus surgical treatment in patients with carotid stenosis in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): a randomised trial. Lancet. 2001;357(9270):1729–1737
  17. Wadhwa K, Oluwale A, Altaf N, Goode S, MacSweeney S, Tennant W. Local anaesthesia versus general anaesthesia for carotid endarterectomy: the Nottingham experience. Cerebrovascular Diseases. 2006;21(S4):151
  18. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TEJ, Johansen-Berg H. Advances in functional and structural MR image analysis and implementation as FSL. In: Conference on mathematics in brain imaging. Los Angeles, CA: Academic Press Inc. Elsevier Science; 2004;
  19. Jenkinson M, Bannister P, Brady M, Smith S. Improved optimization for the robust and accurate linear registration and motion correction of brain images. NeuroImage. 2002;17(2):825–841
  20. Zhang Y, Brady M, Smith S. Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm. IEEE Transactions on Medical Imaging. 2001;20(1):45–57
  21. Goode SD, Krishan S, Alexakis C, Mahajan R, Auer DP. Precision of cerebrovascular reactivity assessment with use of different quantification methods for hypercapnia functional MR imaging. American Journal of Neuroradiology 2009;30(5):972–7.
  22. Baciu M, Juphard A, Cousin E, Bas JF. Evaluating fMRI methods for assessing hemispheric language dominance in healthy subjects. European Journal of Radiology. 2005;55(2):209–218
  23. De Boorder MJ, van der Grond J, van Dongen AJ, Klijn CJ, Jaap Kapelle L, Van Rijk PP, et al. Spect measurements of regional cerebral perfusion and carbondioxide reactivity: correlation with cerebral collaterals in internal carotid artery occlusive disease. Journal of Neurology. 2006;253(10):1285–1291
  24. Kaminogo M, Ochi M, Onizuka M, Takahata H, Shibata S. An additional monitoring of regional cerebral oxygen saturation to HMPAO SPECT study during balloon test occlusion. Stroke. 1999;30(2):407–413
  25. Hosoda K, Fujita S, Kawaguchi T, Shose Y, Shibata Y, Tamaki N. Influence of degree of carotid artery stenosis and collateral pathways and effect of carotid endarterectomy on cerebral vasoreactivity. Neurosurgery. 1998;42(5):988–994
  26. Sfyroeras GS, Arsos G, Karkos CD, Liasidis C, Spyridis C, Boundas D, et al. Interhemispheric asymmetry in brain perfusion before and after carotid stenting: a 99mTc-HMPAO SPECT study. Journal of Endovascular Therapy. 2006;13(6):729–737
  27. Bishop CC, Butler L, Hunt T, Burnand KG. Effect of carotid endarterectomy on cerebral blood flow and its response to hypercapnia. British Journal of Surgery. 1987;74(11):994–996
  28. Haller S, Bonati LH, Rick J, Klarhofer M. Reduced cerebrovascular reserve at CO2 BOLD MR imaging is associated with increased risk of periinterventional ischemic lesions during carotid endarterectomy or stent placement: preliminary results. Radiology. 2008;249(1):251–258
  29. Kastrup A, Dichgans J, Niemeier M, Schabet M. Changes of cerebrovascular CO2 reactivity during normal aging. Stroke. 1998;29(7):1311–1314
  30. Kastrup A, Thomas C, Hartmann C, Schabet M. Sex dependency of cerebrovascular CO2 reactivity in normal subjects. Stroke. 1997;28(12):2353–2356
  31. Matteis MTE, Monaldo BC, Caltagirone C, Silvestrini M. Age and sex differences in cerebral hemodynamics: a transcranial Doppler study. Stroke. 1998;29:963–967
  32. Kimura Y, Oku N, Kajimoto K, Katoh H, Tanaka MR, Takasawa M, et al. Diastolic blood pressure influences cerebrovascular reactivity measured by means of I-123-iodoamphetamine brain single photon emission computed tomography in medically treated patients with occlusive carotid or middle cerebral artery disease. Annals of Nuclear Medicine. 2006;20(3):209–215
  33. Nielsen MY, Sillesen HH, Jorgensen LG, Schroeder TV. The haemodynamic effect of carotid endarterectomy. European Journal of Vascular Endovascular Surgery. 2002;24(1):53–58
  34. Ghogawala Z, Westerveld M, Amin-Hanjani S. Cognitive outcomes after carotid revascularization: the role of cerebral emboli and hypoperfusion. Neurosurgery. 2008;62(2):385–395discussion 393–5
  35. Sander K, Hof U, Poppert H, Conrad B, Sander D. Improved cerebral vasoreactivity after statin administration in healthy adults. Journal of Neuroimaging. 2005;15(3):266–270
  36. Sterzer P, Meintzschel F, Rosler A, Lanfermann H, Steinmetz H, Sitzer M. Pravastatin improves cerebral vasomotor reactivity in patients with subcortical small-vessel disease. Stroke. 2001;32(12):2817–2820
  37. Moody AR, Murphy RE, Morgan PS, Martel AL. Characterization of complicated carotid plaque with magnetic resonance direct thrombus imaging in patients with cerebral ischemia. Circulation. 2003;107(24):3047–3052

PII: S1078-5884(09)00335-9

doi: 10.1016/j.ejvs.2009.06.010

European Journal of Vascular & Endovascular Surgery
Volume 38, Issue 5 , Pages 546-551 , November 2009

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