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Volume 40, Issue 5 , Pages 599-607 , November 2010

Use of B-Type Natriuretic Peptide to Predict Blood Pressure Improvement after Percutaneous Revascularisation for Renal Artery Stenosis

D. Staub
- Department of Angiology, University Hospital Basel, Basel, Switzerland
- First two authors contributed equally to this work.
T. Zeller
- Herz-Zentrum Bad Krozingen, Bad Krozingen, Germany
- First two authors contributed equally to this work.
D. Trenk
- Herz-Zentrum Bad Krozingen, Bad Krozingen, Germany
C. Maushart
- Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
H. Uthoff
- Department of Angiology, University Hospital Basel, Basel, Switzerland
T. Breidthardt
- Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
T. Klima
- Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
M. Aschwanden
- Department of Angiology, University Hospital Basel, Basel, Switzerland
T. Socrates
- Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
N. Arenja
- Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
R. Twerenbold
- Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
A. Rastan
- Herz-Zentrum Bad Krozingen, Bad Krozingen, Germany
S. Sixt
- Herz-Zentrum Bad Krozingen, Bad Krozingen, Germany
A.L. Jacob
- Division of Interventional Radiology, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland
K.A. Jaeger
- Department of Angiology, University Hospital Basel, Basel, Switzerland
C. Mueller
- Department of Internal Medicine, University Hospital Basel, Basel, Switzerland
- Corresponding author. Tel.: +41 61 265 58 26; fax: +41 61 265 5353.

Received 7 May 2010 ,Accepted 19 July 2010.

Flow diagram of patients with renal artery stenosis referred for revascularization.

Flow diagram of patients with renal artery stenosis referred for revascularization.
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Angiographic imaging of renal artery stenosis in two typical cases. Panel A. Ostial atherosclerotic renal artery stenosis (arrow) in a 55-year old woman. The patient had blood pressure improvement (de

Angiographic imaging of renal artery stenosis in two typical cases. Panel A. Ostial atherosclerotic renal artery stenosis (arrow) in a 55-year old woman. The patient had blood pressure improvement (decrease in mean arterial pressure of 10 mmHg) six month after successful renal artery stent placement (panel B) (arrows). BNP level before revascularization was 80 pg/ml and decreased within one day of intervention to 50 pg/ml. Panel B. Renal artery fibromuscular dysplasia showing characteristic ‘string-of-beads’ appearance (arrow) in a 59-year old woman. The patient had blood pressure improvement (clinical cure) six month after angioplasty. BNP level before revascularization was 89 pg/ml and decreased within one day of intervention to 49 pg/ml.
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Median (25th to 75th percentiles) BNP levels before and after percutaneous revascularization for renal artery stenosis in patients with and without blood pressure improvement. *P < 0.001 compared to B

Median (25th to 75th percentiles) BNP levels before and after percutaneous revascularization for renal artery stenosis in patients with and without blood pressure improvement. *P < 0.001 compared to BNP levels pre-intervention, †P < 0.05 compared to BNP levels pre-intervention.
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Percent of patients with blood pressure improvement 6 month after percutaneous revascularization for renal artery stenosis. Pre-intervention BNP >50 pg/ml vs pre-intervention BNP ≤50 pg/ml, and BNP de

Percent of patients with blood pressure improvement 6 month after percutaneous revascularization for renal artery stenosis. Pre-intervention BNP >50 pg/ml vs pre-intervention BNP ≤50 pg/ml, and BNP decrease 1 day after intervention >20 pg/ml vs BNP decrease ≤20 pg/ml.
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