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Letter to the Editor| Volume 61, ISSUE 1, P162-163, January 2021

Comment and Questions on “European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Vascular Graft and Endograft Infections”

  • Philippe Tresson
    Correspondence
    Corresponding author. Department of Vascular and Endovascular Surgery, Hopital Louis Pradel, 28 Avenue Doyen Lepine, 69677 Bron Cedex, France.
    Affiliations
    Department of Vascular and Endovascular Surgery, Hopital Louis Pradel, Bron Cedex, France
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  • Samuel Quiquandon
    Affiliations
    Department of Vascular and Endovascular Surgery, Hopital Louis Pradel, Bron Cedex, France
    Department of Internal Medicine and Vascular Medicine, Groupement Hospitalier Edouard Herriot, Hospices Civils de Lyon, Lyon, France
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  • Anne Long
    Affiliations
    Department of Internal Medicine and Vascular Medicine, Groupement Hospitalier Edouard Herriot, Hospices Civils de Lyon, Lyon, France
    Université de Lyon, University Claude Bernard Lyon 1, Interuniversity Laboratory of Human Movement Biology EA7424, Vascular Biology and Red Blood Cell Team, Villeurbanne, France
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Open ArchivePublished:September 28, 2020DOI:https://doi.org/10.1016/j.ejvs.2020.08.002
      We read with great interest the Clinical Practice Guidelines written by the European Society for Vascular Surgery on the management of vascular graft and endograft infections (VGEI).
      • Chakfé N.
      • Diener H.
      • Lejay A.
      • Assadian O.
      • Berard X.
      • Caillon J.
      • et al.
      Editor's choice - European society for vascular surgery (ESVS) 2020 clinical Practice guidelines on the management of vascular graft and endograft infections.
      The authors developed guidelines to assist physicians involved in the diagnosis and treatment of patient with VGEI.
      Independent patient related risk factors for surgical site infections of the lower limbs are summarised in Table 12 in the paper. We noticed that some results reported in the Guidelines are different from those shown in the cited references (Table 1), and that some other risk factors were not reported.
      Table 1Patient related independent risk factors for surgical site infections of the lower limbs: differences compared with Table 12 of the Guidelines
      • Chakfé N.
      • Diener H.
      • Lejay A.
      • Assadian O.
      • Berard X.
      • Caillon J.
      • et al.
      Editor's choice - European society for vascular surgery (ESVS) 2020 clinical Practice guidelines on the management of vascular graft and endograft infections.
      are highlighted
      Risk factorAdjusted risk estimation – OR (95% CI)Reference
      Female sex1.44 (1.28–1.63)Greenblatt et al.
      • Greenblatt D.Y.
      • Rajamanickam V.
      • Mell M.W.
      Predictors of surgical site infection after open lower extremity revascularization.
      Obesity2.08 (1.78–2.43)Greenblatt et al.
      • Greenblatt D.Y.
      • Rajamanickam V.
      • Mell M.W.
      Predictors of surgical site infection after open lower extremity revascularization.
      BMI ≥ 25 kg/m21.78 (1.23–2.57)

      1.28 (1.10–1.49)
      Davis et al.
      • Davis F.M.
      • Sutzko D.C.
      • Grey S.F.
      • Mansour M.A.
      • Jain K.M.
      • Nypaver T.J.
      • et al.
      Predictors of surgical site infection after open lower extremity revascularization.


      Greenblatt et al.
      • Greenblatt D.Y.
      • Rajamanickam V.
      • Mell M.W.
      Predictors of surgical site infection after open lower extremity revascularization.
      COPD4.29 (2.74–6.72)

      2.10 (1.07–4.09)

      1.23 (1.03–1.43)
      Davis et al.
      • Davis F.M.
      • Sutzko D.C.
      • Grey S.F.
      • Mansour M.A.
      • Jain K.M.
      • Nypaver T.J.
      • et al.
      Predictors of surgical site infection after open lower extremity revascularization.


      Leekha et al.
      • Leekha S.
      • Lahr B.D.
      • Thompson R.L.
      • Sampathkumar P.
      • Duncan A.A.
      • Orenstein R.
      Preoperative risk prediction of surgical site infection requiring hospitalization or reoperation in patients undergoing vascular surgery.


      Greenblatt et al.
      • Greenblatt D.Y.
      • Rajamanickam V.
      • Mell M.W.
      Predictors of surgical site infection after open lower extremity revascularization.
      Dialysis4.35 (3.45–5.47)

      1.51 (1.08–2.11)
      Davis et al.
      • Davis F.M.
      • Sutzko D.C.
      • Grey S.F.
      • Mansour M.A.
      • Jain K.M.
      • Nypaver T.J.
      • et al.
      Predictors of surgical site infection after open lower extremity revascularization.


      Greenblatt et al.
      • Greenblatt D.Y.
      • Rajamanickam V.
      • Mell M.W.
      Predictors of surgical site infection after open lower extremity revascularization.
      CLI4.35 (3.45–5.47)

      2.91 (1.61–5.27)
      Davis et al.
      • Davis F.M.
      • Sutzko D.C.
      • Grey S.F.
      • Mansour M.A.
      • Jain K.M.
      • Nypaver T.J.
      • et al.
      Predictors of surgical site infection after open lower extremity revascularization.


      Leekha et al.
      • Leekha S.
      • Lahr B.D.
      • Thompson R.L.
      • Sampathkumar P.
      • Duncan A.A.
      • Orenstein R.
      Preoperative risk prediction of surgical site infection requiring hospitalization or reoperation in patients undergoing vascular surgery.
      Re-intervention2.91 (1.61–5.27)

      11 (1.9–63)
      Leekha et al.
      • Leekha S.
      • Lahr B.D.
      • Thompson R.L.
      • Sampathkumar P.
      • Duncan A.A.
      • Orenstein R.
      Preoperative risk prediction of surgical site infection requiring hospitalization or reoperation in patients undergoing vascular surgery.


      Brothers et al.
      • Brothers T.E.
      • Robison J.G.
      • Elliott B.M.
      Predictors of prosthetic graft infection after infrainguinal bypass.
      Blood glucose > 11 mmol/L

      Peak glucose >180 mg/dL or > 10 mmol/L
      2.68 (1.38–5.22)

      1.99 (1.53–2.57)
      Leekha et al.
      • Leekha S.
      • Lahr B.D.
      • Thompson R.L.
      • Sampathkumar P.
      • Duncan A.A.
      • Orenstein R.
      Preoperative risk prediction of surgical site infection requiring hospitalization or reoperation in patients undergoing vascular surgery.


      Davis et al.
      • Davis F.M.
      • Sutzko D.C.
      • Grey S.F.
      • Mansour M.A.
      • Jain K.M.
      • Nypaver T.J.
      • et al.
      Predictors of surgical site infection after open lower extremity revascularization.
      Hyponatraemia <134 g/dL11 (1.9–63)

      1.20 (1.02–1.42)
      Brothers et al.
      • Brothers T.E.
      • Robison J.G.
      • Elliott B.M.
      Predictors of prosthetic graft infection after infrainguinal bypass.


      Greenblatt et al.
      • Greenblatt D.Y.
      • Rajamanickam V.
      • Mell M.W.
      Predictors of surgical site infection after open lower extremity revascularization.
      Post-operative immobilisationNone

      1.20 (1.02–1.42)
      None

      Greenblatt et al.
      • Greenblatt D.Y.
      • Rajamanickam V.
      • Mell M.W.
      Predictors of surgical site infection after open lower extremity revascularization.
      Major amputation12 (4.1–34)Brothers et al.
      • Brothers T.E.
      • Robison J.G.
      • Elliott B.M.
      Predictors of prosthetic graft infection after infrainguinal bypass.
      Prior revascularisation2.68 (1.38–5.22)

      1.57 (1.04–2.38)
      Leekha et al.
      • Leekha S.
      • Lahr B.D.
      • Thompson R.L.
      • Sampathkumar P.
      • Duncan A.A.
      • Orenstein R.
      Preoperative risk prediction of surgical site infection requiring hospitalization or reoperation in patients undergoing vascular surgery.


      Davis et al.
      • Davis F.M.
      • Sutzko D.C.
      • Grey S.F.
      • Mansour M.A.
      • Jain K.M.
      • Nypaver T.J.
      • et al.
      Predictors of surgical site infection after open lower extremity revascularization.
      OR = odds ratio; CI = confidence interval; BMI = body mass index; COPD = chronic obstructive pulmonary disease; CLI = critical limb ischaemia.
      We would like to ask authors how they achieved these results and what the criteria were for selecting risk factors.

      References

        • Chakfé N.
        • Diener H.
        • Lejay A.
        • Assadian O.
        • Berard X.
        • Caillon J.
        • et al.
        Editor's choice - European society for vascular surgery (ESVS) 2020 clinical Practice guidelines on the management of vascular graft and endograft infections.
        Eur J Vasc Endovasc Surg. 2020; 59: 339-384
        • Greenblatt D.Y.
        • Rajamanickam V.
        • Mell M.W.
        Predictors of surgical site infection after open lower extremity revascularization.
        J Vasc Surg. 2011; 54: 433-439
        • Davis F.M.
        • Sutzko D.C.
        • Grey S.F.
        • Mansour M.A.
        • Jain K.M.
        • Nypaver T.J.
        • et al.
        Predictors of surgical site infection after open lower extremity revascularization.
        J Vasc Surg. 2017; 65: 1769-1778
        • Leekha S.
        • Lahr B.D.
        • Thompson R.L.
        • Sampathkumar P.
        • Duncan A.A.
        • Orenstein R.
        Preoperative risk prediction of surgical site infection requiring hospitalization or reoperation in patients undergoing vascular surgery.
        J Vasc Surg. 2016; 64: 177-184
        • Brothers T.E.
        • Robison J.G.
        • Elliott B.M.
        Predictors of prosthetic graft infection after infrainguinal bypass.
        J Am Coll Surg. 2009; 208: 557-561

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