Objective
Methods
Results
Conclusion
Keywords
Introduction
- Freiberg M.S.
- Arnold A.M.
- Newman A.B.
- Edwards M.S.
- Kraemer K.L.
- Kuller L.H.
Methods
Study design
NHS Abdominal Aortic Aneurysm Screening Programme. NAAASP Data 2014-2015. https://www.gov.uk/government/publications/abdominal-aortic-aneurysm-screening-2014-to-2015-data. [Accessed 1 January 2016].
Framingham Heart Study. Research results. https://www.framinghamheartstudy.org/fhs-for-researchers/selected-research-results/. [Accessed 1 January 2016].
Definitions
Datasets
The Multi-Aneurysm Screening Study cohort
The NHS AAA Screening Programme cohort
Health Episode Statistics.
Office for National Statistics. Births and Deaths. https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths. [Accessed 1 January 2016].
The Framingham Heart Study cohort
- Hicks K.A.
- Tcheng J.E.
- Bozkurt B.
- Chaitman B.R.
- Cutlip D.E.
- Farb A.
- et al.
Statistical analysis
Results
The Multi-Aneurysm Screening Study

Cause of death | Deaths | Adjusted HR (95% CI) for age | Adjusted HR (95% CI) for competing risk of non-cardiovascular mortality | |
---|---|---|---|---|
Normal aorta n = 25 546 | AAA n = 1 336 | |||
Cardiovascular | 3 423 (13.4) | 325 (24.3) | 2.07 (1.85–2.32) | 2.22 (1.97–2.50) |
Non-cardiovascular | 6 019 (23.6) | 483 (36.2) | 1.78 (1.63-1.96) |
The NHS AAA Screening Programme mortality
Deaths and CV events | HR (95% CI) | Adjusted HR (95% CI) | ||||
---|---|---|---|---|---|---|
≤2.4 cm (reference)n = 231 579 | 2.5–2.9 cm n = 3 228 | ≥3.0 cm n = 2 364 | 2.5–2.9 cm | ≥3.0 cm | 2.5–2.9 cm | |
Deaths | ||||||
CV | 842 (0.36) | 31(0.96) | 35 (1.48) | 2.72 (2.12–3.49) | 3.52 (2.79–4.45) | 2.63 (1.84–3.76) |
Non-CV | 2 045 (0.88) | 48 (1.49) | 51 (2.16) | 1.89 (1.62–2.19) | 2.42 (2.10-2.78) | 1.69 (1.27–2.25) |
Events | ||||||
CV | 18 457 (7.97) | 396 (12.27) | 365 (15.44) | 1.74 (1.55–1.96) | 2.29 (2.05–2.56) | 1.58 (1.43–1.74) |
Non-CV | 49 728 (21.47) | 733 (22.71) | 644 (27.24) | 1.24 (1.17–1.32) | 1.62 (1.53–1.71) | 1.07 (0.99–1.15) |



The NHS AAA Screening Programme major adverse cardiovascular events
The Framingham Heart Study cohort

Discussion
- Freiberg M.S.
- Arnold A.M.
- Newman A.B.
- Edwards M.S.
- Kraemer K.L.
- Kuller L.H.
Limitations
Conclusions
Conflict of interest
Funding
Acknowledgements
Appendix ASupplementary data
Multimedia component 1
- Multimedia component 2
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