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Editor's Choice – Hypothesis for the Increased Rate of Thromboembolic and Microembolic Complications Following Abdominal Aortic Aneurysm Repair in Women

Published:December 29, 2021DOI:https://doi.org/10.1016/j.ejvs.2021.10.046
      Following elective abdominal aortic aneurysm (AAA) repair, both open and endovascular, women appear to be more likely than men to suffer from serious complications, including cardiac and renal problems, bowel, and lower limb ischaemia.
      • Pouncey A.L.
      • David M.
      • Morris R.I.
      • Ulug P.
      • Martin G.
      • Bicknell C.
      • Powell J.T.
      Systematic review and meta-analysis of sex-specific differences in adverse events after open and endovascular intact abdominal aortic aneurysm repair: consistently worse outcomes for women.
      These complications are often attributed to thromboembolic and microembolic events. Could there be a unifying hypothesis or explanation for this relating to the nature of the thrombus within the AAA sac, coupled with more diseased visceral and distal arteries, as previously shown in patients with coronary artery disease (CAD)?
      • Bageacu S.
      • Cerisier A.
      • Isaaz K.
      • Nourissat A.
      • Barral X.
      • Favre J.P.
      Incidental visceral and renal artery stenosis in patients undergoing coronary angiography.
      A pilot single centre study was undertaken to test this hypothesis and investigate sex specific morphological differences in the aortic thrombus, visceral and distal arteries.

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      References

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