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Compression Hosiery to Avoid Post-Thrombotic Syndrome (CHAPS) Trial

Published:August 08, 2022DOI:https://doi.org/10.1016/j.ejvs.2022.07.056
      Worldwide approximately half of adults diagnosed with deep vein thrombosis (DVT) of the lower limb will go on to develop the post-thrombotic syndrome (PTS). PTS is defined as chronic venous symptoms or signs secondary to DVT, including leg pain, oedema, venous ectasia, and in 5% of patients progressing to venous ulceration.
      • Kahn S.R.
      • Partsch H.
      • Vedantham S.
      • Prandoni P.
      • Kearon C.
      Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of post-thrombotic syndrome of the leg for use in clinical investigations: a recommendation for standardization.
      Despite adequate anticoagulation, PTS remains a chronic health condition with significant financial burden for both patients and health services.
      • Bergqvist D.
      • Jendteg S.
      • Johansen L.
      • Persson U.
      • Odegaard K.
      Cost of long-term complications of deep venous thrombosis of the lower extremities: an analysis of a defined patient population in Sweden.

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